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Patient-Reported Symptom Burden in Women Undergoing Treatment for Early-Stage and Metastatic Breast Cancer

By December 9, 2022No Comments
Poster: Patient-Reported Symptom Burden in Women Undergoing Treatment for Early-Stage and Metastatic Breast Cancer

Authors: Tara L. Kaufmann, MD MSCE1,Aaron Galaznik, MD2 , Nicholas Coombs, PhD, MSTAT3 , Gabrielle Betty Rocque MD, MSPH4

1University of Texas at Austin – Austin, TX, 2Carevive Systems, IncTM, 3Piedmont Research Strategies, Inc., 4University of Alabama at Birmingham – Birmingham, AL


Women undergoing treatment for breast cancer experience both disease- and treatment-related symptoms. Remote symptom management (RSM) programs allow real-time symptom documentation, earlier intervention, and opportunities to improve quality of life and decrease symptom burden. Prior studies have focused on the supportive care needs of women with advanced breast cancer.


The objective of this study is to describe patient-reported outcomes (PROs) in women undergoing treatment for early-stage and metastatic breast cancer.


Study Design

This was a feasibility study gathering PROs with real-world data among a cohort of patients with breast cancer using a remote symptom monitoring platform.


  • Women aged 18 years or older receiving treatment for breast cancer
  • At least 12 planned treatments
  • Access to Smart phone, tablet or computer


Patient Reported Outcomes Mobile Platform (PROmpt®), an application for remote patient reporting and provider symptom management

Data Collection

  • After consent, patients were enrolled in PROmpt® and completed baseline surveys
  • Weekly assessments included symptom burden of 14 common symptoms (PRO-CTCAE)
  • Clinical data were obtained from electronic medical record structured data


Descriptive analyses summarized PROs for early-stage (stage I-III) and metastatic (stage IV) patients. Symptom burden was assessed by calculating the frequency distribution of each patient’s highest reported composite score for each symptom by month.


See poster image for results.


  • Women with metastatic and early-stage breast cancer both report severe symptoms during treatment.
  • Early-stage patients may have different symptom profiles and unmet needs not captured by common PROs.
  • Future work should further evaluate symptom profiles of early-stage patients to understand how to best use
Poster: Patient-Reported Symptom Burden in Women Undergoing Treatment for Early-Stage and Metastatic Breast Cancer

Click on image to enlarge


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